Stem Cell Biology
Medical Faculty Carl Gustav Carus Dresden
Stem cell research in degenerative disease and cancer

About us

Welcome to our laboratory’s site. Here you can find information about our research, our scientific approach, and news. Our research efforts involve two locations: Dresden, and Rome. In Dresden, we belong to the University hospital, and specifically the Medical Clinic III, where we run the “Stem Cell Biology” lab. In addition, we are members of the Center for regenerative Therapies Dresden (CRTD), located on the same campus. In Rome, we are part of the European Brain research Institute (EBRI), headed by Rita Levi-Montalcini. Our lab at EBRI is the “Stem Cells” lab.

So, we like stem cells. We do, because we see promise in them, both as exceptional tools to study biology in as well as mediators of tissue regeneration. There are many types of stem cells, some that can regenerate the tissue they reside in, some that can generate cells from multiple tissues, and some that can generate an entire organism. And there are many research approaches, including transplanting these cells after they are grown in large numbers in culture, or targeting the existing (endogenous) stem cells in the tissue, using drugs. The latter is our main goal, and the central nervous system (brain and spinal cord) is our primary tissue of focus. But here and there, we look elsewhere too, when we cannot resist our curiosity.

Our experimental approach is influenced by our past discoveries that the adult brain is rich in immature cells (neural stem cells), and that they can be activated by soluble factors acting through a novel biochemical pathway. This leads to powerful neuronal rescue and motor skill benefits.

We have only recently started our endeavor, and we are in the process of expanding our size, but we are already running projects that are exciting us. Much of this relies on collaborations with colleagues in Dresden and Rome who have given us great help and support. In the RESEARCH tab you can find a somewhat more scientific description of our research interests.

Universitätsklinikum Carl Gustav Carus
an der Technischen Universität Dresden,
Department of Medicine III,
Fetscherstr. 74, 01307 Dresden
Haus 10, Zimmer 409
Office: +49 (0)351 458 4978
Lab: +49 (0)351 458 6615
Medical Faculty Carl Gustav Carus Dresden Lab page

European Brain Research Institute (EBRI)
Via del Fosso di Fiorano 64
00143 Roma, Italia
Web: http://www.ebri.it/en/research/laboratories/stem-cells/